JOB SUMMARY:
An opportunity has arisen in the formulation department to assist in the development of both topical pharmaceutical (for OTC and ethical markets) and cosmetic products. The position will include laboratory-scale formulation development, the scale-up of potential formulations in our pilot facility, and involvement with technology transfer of development products into commercial manufacture in accordance with GMP. Some travel may be required between sites.
OBJECTIVES AND PURPOSE OF THE POST:
1.1Formulation Development for New and Existing Products
To prepare a range of new product formulations (creams, gels, lotions, shampoos) and monitor them for physical/emulsion stability, pH and viscosity to find the optimum formulation. As part of this development work new materials will require sourcing in-line with current guidelines/directives. Pharmaceutical development reports will require writing and updating for each project.
Formulation Development work will also be required to support and improve Existing Product lines, where necessary. Product line extensions will also be investigated.
1.2Preparing supplies of Development Products for Accelerated Stability Studies
Formulations which have passed the initial screening process will need to be manufactured on a small scale for accelerated stability trials in a range of packaging materials; these will be screened by the analytical laboratory for both chemical and physical stability.
1.3Preparing supplies of Development Products for Stability/Clinical Studies
Formulations selected from the accelerated screening programme are manufactured on a larger scale (up to 100 kg) at our pilot facility at Kempston. The position will include assisting in the dispensing, manufacture and filling of pilot-scale batches for stability/clinical trials. This will involve working to GMP and manual lifting. Data generated from these trials is used for the Product Licence application.
The position will include the labelling and presentation of supplies for clinical trials.
OBJECTIVES AND PURPOSE OF THE POST (cont.):
1.4Environmental Monitoring
On an occasional basis, environmental plates and water sample will require monitoring and reporting.
1.5Data Handling
Ability to use computer software packages, such as LIMS, Excel and Word for processing and reporting of data.
1.6Day-to-Day running of the Formulation Laboratory
Take equal part in the overall running of the Formulation Laboratory, including equipment maintenance, calibration of apparatus and other general duties such as solvent disposal.
1.7To bring to the attention of his/her immediate superior any difficulties or problems encountered in the performance of his/her duties.
1.8To be aware of the safety regulations in operation in the department, and in the light of the Health and Safety at work act, to perform his/her duties in such a manner so as not to endanger the safety and health of his/her fellow workers.
1.9To perform other scientific and technical duties as requested.
SKILLS REQUIRED (after suitable training):
The ideal candidate would have a degree/diploma or equivalent in a scientific discipline. Formulation experience, preferably in pharmaceuticals/cosmetics or other skincare products and an appreciation of working in a GMP environment are required.
GENERAL:
To comply at all times with any regulations issued by the Company, especially those governing Health and Safety at work, and to ensure that any defects that may affect safety at work are brought to the attention of the appropriate manager.
This job description reflects the present requirements of the post. It does not form part of the contract of employment. As the duties of the post change and develop, the job description will be reviewed and will be subject to amendment in consultation with the postholder.
CONFIDENTIALITY:
All staff are required to respect the confidentiality of all matters that they may learn relating to their employment, Company business and other members of staff. All staff are expected to respect the requirements under the Data Protection Act 1998
To apply for this position, candidates must be eligible to live and work in the UK
Formulation, Hertfordshire, GMP, GLP, process, manufacturing
Matchtech Group Plc is acting as an Employment Agency in relation to this vacancy.