World Science Jobs

The Immunology group is seeking an experienced and highly motivated Research Associate/Senior Research Associate to identify, evaluate and characterize molecular targets for the treatment of malignancies and autoimmune diseases. The successful candidate will utilize in vivo animal models and a wide range of in vitro approaches to understand the efficacy and the role of molecular targets in immune cell function in the context of therapeutic intervention.

Qualifications:
- BS or MS with a minimum of four years hands-on relevant research experience.
- A proven working knowledge of a wide range of cellular and biochemical assays, cell isolation and culture, flow cytometry and state-of-the-art molecular biology techniques is required.
- Experience in animal models of disease is desirable as well as experience working in the oncology therapeutic area.
- Qualified candidates will have the proven ability to work independently.
- Solid written and verbal communication skills as well as organizational skills are essential.

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act.

All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague’s long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer’s support of a colleague’s temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the “at-will” employment relationship between the colleague and Pfizer.

Benefits:

Throughout our 153 years, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when it comes to our employees. Pfizer wants to ensure that employees have resources to help them develop and succeed both in their careers and personal lives. One way we can achieve this is
through our comprehensive benefits program, which offers employees and their eligible dependents the variety and flexibility to help address their needs at different stages in life.

Company Profile:

Rinat, located in South San Francisco, is now part of the Pfizer Biotherapeutics and Bioinnovation Center (BBC). The center works both independently and interdependently with Pfizer Global Research and Development (PGRD), creating and overseeing a federation of units and collaborations with the academic, biomedical, biotech communities, while collaborating closely with PGRD to discover and develop protein therapeutics that address significant unmet medical needs.

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The Principal Scientist position in the Target Generation Unit (TGU) of the Biotherapeutics and Bioinnovation Center (BBC) is responsible for implementing a strategy to identify novel drug targets by discovering rare human DNA sequence variants associated with adverse clinical outcomes. The successful candidate will have a broad understanding of DNA sequencing technologies, and familiarity with analytical techniques for DNA characterization. The successful candidate will apply technical and functional knowledge to design experiments and independently complete work. Significant experience applying DNA sample preparation studies and engineering principles to reduce the time and cost of high-throughput DNA sequencing is essential. The incumbent must have demonstrated productivity in a dynamic collaborative environment. Effective communication skills are essential for directing laboratory scientists and technicians.

Qualifications:
Ph.D. plus >3 years of work experience with high-throughput, single molecule DNA sequencing in the biotechnology industry required. Theoretical and practical knowledge of diverse DNA sample preparation techniques required. Excellent written and verbal communications skills. Demonstrated capability to perform independent research. A strong work ethic, team player and willingness to take on challenging tasks are also required.

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act.

All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague’s long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer’s support of a colleague’s temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the “at-will” employment relationship between the colleague and Pfizer.

Benefits:

Throughout our 153 years, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when it comes to our employees. Pfizer wants to ensure that employees have resources to help them develop and succeed both in their careers and personal lives. One way we can achieve this is
through our comprehensive benefits program, which offers employees and their eligible dependents the variety and flexibility to help address their needs at different stages in life.

Company Profile:

At the Biotherapeutics and Bioinnovation Center (BBC), Pfizer’s independent biotechnology research division, we’re dedicated to looking at diseases in novel ways and discovering new medicines for patients suffering from life-threatening and life-altering diseases. The BBC is a federation of independent research units, each focused on a novel and growing area of biotechnology and utilizing it to develop and deliver a steady pipeline of biotherapeutics. The Target Generation Unit (TGU), located in South San Francisco, is one of the units, which works together with Pfizer Global Research and Development (PGRD) to discover and develop these new medicines, as to improve wellness and quality of life across a range of therapeutic areas.

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Shape Your Future And Ours.

Schering-Plough is an innovation-driven, science-centered global health care company. Through our own biopharmaceutical research and collaborations with partners, we create therapies that help save and improve lives around the world. We apply our research-and-development platform to human prescription and consumer products as well as to animal health products. Schering-Plough’s vision is to “Earn Trust, Every Day” with the doctors, patients, customers and other stakeholders served by our colleagues around the world.

Director, Health Outcomes
Requisition Number: 22332BR

Description:

Reporting to the Executive Director, the position will be responsible for leading the design, implementation and interpretation of strategies and activities associated with health economic and outcomes research to support the Global Pharmaceutical Business units and Schering-Plough Research Institute. In performing this function, alignment and coordination with interdisciplinary clinical research, medical affairs and commercial functions throughout the SP organization, as well as identify and interface with a variety of clinical and academic investigators, key thought leaders, and health economic and outcomes research contract agencies throughout the world.

Major activities and responsibilities include but are not limited to:

- The Global Health Outcomes (GHO) group works to demonstrate, document, and communicate the value of SP products throughout the lifecycle to support pricing, access and marketing efforts. GHO amplifies and translates clinical benefit into meaningful value propositions for diverse stakeholders and values the clinical impact of disease and healthcare interventions and helps communicate this value to these stakeholders. The GHO group reports to the Group VP of Global Market Access within SP’s Global Pharmaceutical Business.

- Lead the development and implementation and interpretation of health outcomes and economic strategies and tactics supporting the Global Pharmaceutical Business units and Schering-Plough Research Institute.

- Responsible for the overall quality, applicability and timely output of health outcomes and economic activities.

- Responsible for the development of materials to support product access and reimbursement. Must have in-depth knowledge of global health care access and reimbursement systems, including managed care organizations, CMS, HTA bodies.

- Responsible for demonstrating SP’s Leader Behaviors, such as, shared accountability and transparency; cross-functional teamwork and collaboration; listening and learning; benchmark and continuously improve; coaching and leading others; and business integrity.

- This position will be responsible for leading and mentoring junior level staff.

Qualifications:
- Doctoral degree (PhD, Dr.PH, ScD) in health services research, public health, epidemiology, or health economics or a Doctoral degree in a clinical discipline (medicine, pharmacy, nursing) with a Masters degree (MSc, MPH) in health services research, public health, epidemiology, or health economics.

- At least 5+ years of experience working in health outcomes research. Industry experience across multiple phases of product development and global experience required.

- In-depth knowledge in the following: pharmacoepidemiology, pharmacoeconomics, patient reported outcomes, health technology assessments, evidence base medicine research, comparative effectiveness research, clinical research and clinical study design.

- Prior people supervisory experience preferred.

- Excellent interpersonal skills required. Demonstrated ability to understand and respond to multiple internal and external stakeholder needs. Ability to handle conflict constructively, negotiate, and influence with limited supervisory support.

- Ability to exercise good triage and judgment to manage a significant volume of activities with potential competing timelines.

- Publication and presentation track record.

- Excellent oral and written English communication skills.

Schering-Plough is an equal opportunity employer. M/F/D/V

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Faculty Opportunities at the Interface of Biochemistry and Bioclinical Science

The Departments of Biochemistry and Molecular Biology, Surgery, Medicine, and Radiation Oncology at the University of Chicago invite applications from investigators working at the biochemical- clinical science interface for two tenure track faculty positions. Rank will be determined by qualifications. We seek creative, independent, and collaboratively-minded scientists who are actively pioneering novel approaches and technologies to be applied within the continuum of molecular and clinical experimentation. Areas of interest include but are not limited to synthetic biology, structural biochemistry, analysis of mechanisms of biological signaling and transport, analysis of protein association and aggregation, synthesis of self-assembling bioartificial materials, cell-matrix interactions, and other important biological problems. Ph.D. or M.D. with postdoctoral experience required.

Primary appointment will be in the Department of Biochemistry and Molecular Biology with secondary appointment in one or more of the clinical departments. Successful candidates will be provided with a generous start-up package and research space in the newly-constructed Knapp Center for Biomedical Discovery, and will be expected to develop a well-funded robust and collaborative research program. Applications must include curriculum vitae, list of publications, summary of past accomplishments, and plan for future research. Applicants must also arrange for three letters of reference to be directly sent.

Please submit applications and letters by December 15, 2008 to: Chair, Faculty Search Committee, Department of Biochemistry and Molecular Biology, 929 E. 57th Street, Room W225, Chicago, IL 60637. The University of Chicago is an Affirmative Action/Equal Opportunity Employer.

INDIANA UNIVERSITY SCHOOL OF MEDICINE
Department of Anesthesia

The Department of Anesthesia, Indiana University School of Medicine (IUSM), is pleased to seek applications for the V. K. Stoelting Professorship in the area of pain and neurobiology research. This endowed professorship honors the late founding chairman of the IUSM Department of Anesthesia. This search reflects a multidisciplinary commitment on the part of Indiana University to expand upon an excellent basic pain
research program within the University and Medical School. Projects by other funded principal investigators within the group include signaling pathways mediating sensitivity of sensory neurons, endocannabinoids, and sodium, potassium, and TRP channels. Transgenic, gene-targeting, confocal microscopy, proteomics, and mass
spectrometry core facilities are available. The successful candidate will occupy state-of-the-art laboratory space that will expand in the next five years as several research buildings under construction are completed.
Candidates with research interests in basic or translational pain research are encouraged to apply. Successful applicants are expected to maintain a strong, independent, extramurally-funded research program and to participate in educating students, residents, and fellows. Highly competitive salary, startup funds, and space will be provided. Applicants must have a PhD and/or MD degree (or equivalent) and research accomplishments that would merit appointment as a named professor at IUSM. The search committee will begin considering applications immediately and on an on-going basis until the position is filled.

Applicants should submit a curriculum vitae, a
summary of past accomplishments and future plans, and the names and email addresses of three references electronically to phtxjobs@iupui.edu or by post to: V. K. Stoelting Professorship Search Committee, c/o Michael R. Vasko, Ph.D., Paul Stark Professor and Chair, Department of Pharmacology and Toxicology, IU School of Medicine Indianapolis, IN 46202.

Indiana University is an EEO/AA Employer, M/F/D.

The Pharmaceutical Formulation Scientist will develop parenteral research formulations including nanoparticle formulations comprised of novel polymers, liposomes, dendrimers and macromolecular siRNA-conjugates . The candidate will be expected to perform experimental formulation development work, to characterize formulations, to document results and to provide updates at departmental meetings and in reports. Candidate will be an integral part of a research team involved in the screening and subsequent development of a parenterally administered siRNA formulation.

The Pharmaceutics/ Formulation Scientist will develop parenteral research formulations including nanoparticle formulations comprised of novel polymers, liposomes, dendrimers and macromolecular siRNA-conjugates . The candidate will be expected to perform experimental formulation development work, to characterize formulations, to document results and to provide updates at departmental meetings and in reports. Candidate will be an integral part of a research team involved in the screening and subsequent development of a parenterally administered siRNA formulation.

Ideal candidates will have a Ph.D in pharmaceutical sciences and at least two years experience in formulations or product development work for nucleic acids. Ideally the incumbent will have experience in parenteral formulations of biologics, nucleic acids, or traditional parenteral drug formulations. Knowledge of polymers, nucleic acids is desirable, as is experience and interpretive skills in various analytical techniques, e.g. DLS, calorimetry, HPLC, PAGE, MS.

A high level of creativity, self-motivation, attention to detail, and scientific reasoning is required. Familiarity with GMP, understanding of regulatory requirements and prior experience in helping with regulatory submission (IND, NDA) is an advantage. Ability to perform as an individual contributor and as a team member, good interpersonal skills, and strong work ethic are expected.

Throughout our 153 years, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when it comes to our employees. Pfizer wants to ensure that employees have resources to help them develop and succeed both in their careers and personal lives. One way we can achieve this is through our comprehensive benefits program, which offers employees and their eligible dependents the variety and flexibility to help address their needs at different stages in life.

“Headquartered at the RTC, and comprising research groups in Cambridge and Düsseldorf, the goal of our RNAi Therapeutics Group is clear – delivering RNAi therapies to meet our patients’ needs. Our mission is to develop the therapeutic applications of RNAi, and to apply innovative science to solve the difficulties inherent in RNAi therapeutics. Applying our capabilities across a broad range of technologies, our mission combines the best of both worlds – the challenges inherent in solving basic research problems, and the excitement of therapeutic research and development.

Our Chief Scientific Officer, Dr. Art Krieg, Chief inventor of CpG Technology, plans on building a team of elite RNAi scientists who will work on solving the challenges of RNAi delivery to provide the fullest possible clinical benefit of this technology platform. At Pfizer we believe that we have the opportunity to apply Pfizer’s research capabilities to RNAi. We have access to exceptional therapeutic area expertise that from inside and outside the company, we can apply internal and external resources to tackle the significant issues that are must be overcome to realize the full potential benefit in RNAi.

The new RNAi research center provides the perfect opportunity to combine innovative minds with cutting edge technologies and to apply both to help us end disease and forever change the way we improve the health and well-being of all people.”

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Shape Your Future And Ours.

Schering-Plough is an innovation-driven, science-centered global health care company. Through our own biopharmaceutical research and collaborations with partners, we create therapies that help save and improve lives around the world. We apply our research-and-development platform to human prescription and consumer products as well as to animal health products. Schering-Plough’s vision is to “Earn Trust, Every Day” with the doctors, patients, customers and other stakeholders served by our colleagues around the world.

Senior Director, Global Compliance & Business Practices
Requisition Number: 22820BR

Description:
Reports to Vice President, Global Compliance & Business Practices and provides support to President, regional and country management teams for Animal Health. This position is responsible for the co-development and implementation of the Company’s Global Compliance function for Intervet/Animal Health through close interaction with Regional and local country management teams and Regional Compliance teams. Directly supervises a full-time Compliance Director and works closely with Regional Compliance Directors.

The primary purpose of the position is to work as a key member and resource for the corporate (located in Boxmeer Netherlands) and regional management teams in six regions of the world. Particular focus is placed on ensuring that country operations have integrated compliance programs and activities into the business operations and that there is accountability and transparency for compliance at the local country operations.

The function, through a risk-based approach helps embed business integrity and compliance behavior into the Regional and local country business operations, in an effective and efficient manner. The primary objective is to advise regional and country management on the required elements of compliance programs and ensure that country management teams establish and sustain an effective compliance program in country. The position will provide leadership and best practices to the regional management and regional compliance teams and make regulars with country visits and regular communications with these colleagues. Works closely with the business and compliance colleagues, as well as Global Law, Global Finance, and the Global Internal Audit function. The position also, acts as a coordinator and catalyst for corporate compliance initiatives into the local/regional operations, and leads, directs or participates in regional and local initiatives and projects as appropriate and necessary.

As a senior staff member, the individual must have the appropriate level of business and compliance experience, as well as executive presence, to advise management on complex business process and compliance related issues and to communicate issues and action plans through the operation.

Schering-Plough is an equal opportunity employer. M/F/D/V

Click HERE to Apply: http://www.airspartner.com/jpartner/schering_plough.home?_jobPostingID=379510